Background: Lumbosacral plexopathies are rare and may develop as a result of various pathologies. The most common causes of lumbosacral plexopathy include infiltrative infections such as herpes zoster, parturition, tumors, postoperative complications of abdominopelvic surgery, and ischemic vascular injury resulting from intramuscular injections. Treatment is based on the etiology and the severity of the pain.

Findings: We describe herein the evaluation and treatment of a 37-year-old female patient who was admitted with complaints of pain in her left hip and sciatic nerve traces.

Conclusions: Pain resulting from lumbosacral plexopathy is a difficult diagnosis. Keys to the diagnosis include a clinical picture disproportional to lumbar-sacral magnetic resonance image findings. Treatment is determined by the etiology.